Disrupt your market

Disrupt your market

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250X Size Reduction

Through precise control of reaction conditions and by effortlessly attaining high cell densities, we achieve a compact, high productivity bioreactor. Switch to us and save on hardware, real estate and operating costs!

250X Size Reduction

Through precise control of reaction conditions and by effortlessly attaining high cell densities, we achieve a compact, high productivity bioreactor. Switch to us and save on hardware, real estate and operating costs!

250X Size Reduction

Through precise control of reaction conditions and by effortlessly attaining high cell densities, we achieve a compact, high productivity bioreactor. Switch to us and save on hardware, real estate and operating costs!

One-Step Scale Up

The difference between a lab-scale spiral bioreactor and an industrial-scale one is the number of independent spiral channels that the devices harbour, meaning process KPIs observed in a single-channel lab bioreactor will remain the same when transferring it to a multi-channel industrial bioreactor, removing the need for scale-up studies and accelerating your process readiness.

One-Step Scale Up

The difference between a lab-scale spiral bioreactor and an industrial-scale one is the number of independent spiral channels that the devices harbour, meaning process KPIs observed in a single-channel lab bioreactor will remain the same when transferring it to a multi-channel industrial bioreactor, removing the need for scale-up studies and accelerating your process readiness.

One-Step Scale Up

The difference between a lab-scale spiral bioreactor and an industrial-scale one is the number of independent spiral channels that the devices harbour, meaning process KPIs observed in a single-channel lab bioreactor will remain the same when transferring it to a multi-channel industrial bioreactor, removing the need for scale-up studies and accelerating your process readiness.

No Seed Train

The compactness of our bioreactor means that your usual and often expensive seed train procedure will not surpass a petri dish and a shake-flask culture, saving you time, money and effort!

No Seed Train

The compactness of our bioreactor means that your usual and often expensive seed train procedure will not surpass a petri dish and a shake-flask culture, saving you time, money and effort!

No Seed Train

The compactness of our bioreactor means that your usual and often expensive seed train procedure will not surpass a petri dish and a shake-flask culture, saving you time, money and effort!

No Mechanical Stirring

Why mix your culture if it does that by itself? Convective stirring during culture media flow ensures optimal mass transfer between the 3 phases (gas, culture media, cells) without the need for mechanical stirring, giving you improved mixing for a fraction of the energy!

No Mechanical Stirring

Why mix your culture if it does that by itself? Convective stirring during culture media flow ensures optimal mass transfer between the 3 phases (gas, culture media, cells) without the need for mechanical stirring, giving you improved mixing for a fraction of the energy!

No Mechanical Stirring

Why mix your culture if it does that by itself? Convective stirring during culture media flow ensures optimal mass transfer between the 3 phases (gas, culture media, cells) without the need for mechanical stirring, giving you improved mixing for a fraction of the energy!

We Sell

We Sell

We Sell

Bioreactors or

Bioreactors or

Bioreactors or

Production time

Production time

Production time

Our Story

From the far East, West and Centre of the globe, Spironix’s team members discover their shared aspiration and passion for biomanufacturing and decide to manifest it by sharing a small office at the University of Sheffield’s Chemical and Biological Engineering Department. One room, one whiteboard and three desks later, we find ourselves drafting the future of the bioindustry using a bold and radically different version of the Bioreactor.

Combining mechanical engineering, synthetic biology and business development expertise, we set out to show the world that better ways of manufacturing that do not compromise the environment for the sake of efficiency exist!

This webpage is our team’s first attempt to communicate its message to the world and to listen to what the world has to say back to us. We aim to understand the pharmaceutical, fragrances, flavours and in general, the speciality chemicals sector to tailor our solution to these industries.

The Problem

The Problem

Biotechnology has the potential to play a key role in supporting the chemicals industry in operating sustainably and in reaching net-zero carbon emissions. Currently, however, biotechnology is seen by the chemicals industry as being costly and inefficient. Therefore, biotechnology is restricted to producing low volume but high value chemicals such as vaccines and therapeutic proteins. One major reason for the cost and inefficiency associated with biotechnology is that existing industrial bioreactor technologies are based on reactors originally developed for simpler chemical reactions and don't fully take into account one key difference - living cells adapt!  

Our Vision

Our Vision

Our vision is to make biotechnology a viable route for manufacturing a wide spectrum of chemicals from the humble ethanol to the blockbuster monoclonal antibodies while simultaneously enabling the chemicals industry to operate sustainably and reach net zero emissions. To achieve our vision, we are radically reinventing the bioreactor by moving away from the stirred tank bioreactor operating under gravity towards a spiral bioreactor operating under centrifugal force. 

Operating in a spiral

Operating in a spiral

At the heart of our technology is a spiral channel maintained under centrifugal acceleration due to rotation. The centrifugal force physically immobilises the cells (or even enzymatic particles!) in the spiral channel creating a catalytic bed with high cell densities in the bioreactor. A precisely controlled flow of reagents, nutrients and gas (oxygen for aerobic reactions) over the bed, allows continuous product generation whilst nourishing the cells. Excellent control over mass transfer ensures a stable environment for the cells resulting in demonstrated enhancements in productivity in our rotating spiral bioreactor relative to the conventional stirred tank bioreactors.

Our Team

Entrepreneurial Lead

Ahmed Tamer Dahraoui

A student of Dr. Karunakaran and Dr. MacInnes, Ahmed conducts his Masters thesis on antibiotic production in the Rotating Spiral and comes to understand the true potential of the device. Believing in the duo’s technology and competency and having previous entrepreneurial experience in classic businesses, he joins the team as the entrepreneurial lead to set the foundations of the company, raise funding and accelerate its growth.

Entrepreneurial Lead

Ahmed Tamer Dahraoui

A student of Dr. Karunakaran and Dr. MacInnes, Ahmed conducts his Masters thesis on antibiotic production in the Rotating Spiral and comes to understand the true potential of the device. Believing in the duo’s technology and competency and having previous entrepreneurial experience in classic businesses, he joins the team as the entrepreneurial lead to set the foundations of the company, raise funding and accelerate its growth.

Entrepreneurial Lead

Ahmed Tamer Dahraoui

A student of Dr. Karunakaran and Dr. MacInnes, Ahmed conducts his Masters thesis on antibiotic production in the Rotating Spiral and comes to understand the true potential of the device. Believing in the duo’s technology and competency and having previous entrepreneurial experience in classic businesses, he joins the team as the entrepreneurial lead to set the foundations of the company, raise funding and accelerate its growth.

Engineering Scientific Lead

Dr. Jordan MacInnes

With 35 years of fluid mechanics experience under his belt, Jordan has spent the last 15 years of his career developing our proprietary Rotating Spiral Technology for different use cases. Recognising it’s potential, he decides to focus on adapting the Rotating Spiral for biomanufacturing use as a bioreactor. Jordan now oversees the technology’s development to a commercially viable device that maximises the potential of any cell strain or enzyme.

Engineering Scientific Lead

Dr. Jordan MacInnes

With 35 years of fluid mechanics experience under his belt, Jordan has spent the last 15 years of his career developing our proprietary Rotating Spiral Technology for different use cases. Recognising it’s potential, he decides to focus on adapting the Rotating Spiral for biomanufacturing use as a bioreactor. Jordan now oversees the technology’s development to a commercially viable device that maximises the potential of any cell strain or enzyme.

Engineering Scientific Lead

Dr. Jordan MacInnes

With 35 years of fluid mechanics experience under his belt, Jordan has spent the last 15 years of his career developing our proprietary Rotating Spiral Technology for different use cases. Recognising it’s potential, he decides to focus on adapting the Rotating Spiral for biomanufacturing use as a bioreactor. Jordan now oversees the technology’s development to a commercially viable device that maximises the potential of any cell strain or enzyme.

Engineering Scientific Lead

Dr. Esther Karunakaran

Esther Karunakaran is a synthetic biologist with a focus on biofilm research. After spending 15 years in the field, she meets Dr. MacInnes and decides to cooperate with him on a grant to see how would cells preform in his quirky and newly developed spiral device. To their surprise, the cells productivity skyrockets and they rest is history. Esther is now responsible for the full adaptation of the Rotating Spiral for the needs of cells and enzymes.

Engineering Scientific Lead

Dr. Esther Karunakaran

Esther Karunakaran is a synthetic biologist with a focus on biofilm research. After spending 15 years in the field, she meets Dr. MacInnes and decides to cooperate with him on a grant to see how would cells preform in his quirky and newly developed spiral device. To their surprise, the cells productivity skyrockets and they rest is history. Esther is now responsible for the full adaptation of the Rotating Spiral for the needs of cells and enzymes.

Engineering Scientific Lead

Dr. Esther Karunakaran

Esther Karunakaran is a synthetic biologist with a focus on biofilm research. After spending 15 years in the field, she meets Dr. MacInnes and decides to cooperate with him on a grant to see how would cells preform in his quirky and newly developed spiral device. To their surprise, the cells productivity skyrockets and they rest is history. Esther is now responsible for the full adaptation of the Rotating Spiral for the needs of cells and enzymes.

Conact us

Contact us

Contact us